2024
High-dimensional in situ proteomics imaging to assess γδ T cells in spatial biology
J Leukoc Biol. 2024 Jan 29
Reprogramming of human γδ T cells by expression of an anti-CD19 TCR fusion construct (εTRuC) to enhance tumor killing
J Leukoc Biol. 2024 Jan 19;115(2):293-305
Vdelta1 T cells are more resistant than Vdelta2 T cells to the immunosuppressive properties of galectin-3
Front Immunol. 2024 Jan 8:14:1286097
2023
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells
Nat Immunol. 2023 Nov 27. doi: 10.1038/s41590-023-01665-0.
A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human γδ T cell phosphoantigen sensing
Nat Commun. 2023 Nov 22;14(1):7617
γδ T cells: origin and fate, subsets, diseases and immunotherapy
Signal Transduct Target Ther. 2023 Nov 22;8(1):434.
Engineering of an Optogenetic T Cell Receptor Compatible with Fluorescence-Based Readouts
ACS Synth Biol. 2023 Oct 20;12(10):2857-2864
RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery
Cell Rep. 2023 Oct 9;42(10):113230
Transcriptomic profile of TNFhigh MAIT cells is linked to B cell response following SARS-CoV-2 vaccination
Front Immunol. 2023 Jul 26:14:1208662
High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production
Cell Rep. 2023 Jul 25;42(7):112713
Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression
J Leukoc Biol. 2023 Jul 12:qiad069
Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands
Cancer Immunol Res. 2023 Jun 2;11(6):810-829
Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency
Front Immunol. 2023 Apr 18;14:1128326
Phosphoantigen sensing combines TCR-dependent recognition of the BTN3A IgV domain and germline interaction with BTN2A1
Cell Rep. 2023 Mar 28;42(4):112321
A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages
Cell Rep. 2023 Mar 14;42(3):112253
Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions
Front Mol Biosci. 2023 Feb 20:10:1143274
Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Proc Natl Acad Sci USA. 2023 Jan 3;120(1):e2210490120
2022
OMIP-084: 28-color full spectrum flow cytometry panel for the comprehensive analysis of human γδ T cells
Cytometry Part A. 2022 Oct;101(10):856-861.
Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Front Immunol. 2022 Sep 27:13:960920
Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells
Cell Mol Life Sci. 2022 Sep 12;79(10):513
A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR
J Exp Med. 2022 Sep 5;219(9):e20212525.
Phenotypic and functional analysis of gd T cells in the pathogenesis of human T-cell lymphotropic virus type 1 infection
Front Immunol. 2022 Aug 11;13:920888.
New insights on murine γδ T cells from single-cell multi-omics
Sci Bull (Beijing). 2022 Jun 15;67(11):1102-1104
δ T cells license immature B cells to produce a broad range of polyreactive antibodies
Cell Rep. 2022 May 24; 39(8):110854.
Integrin activation enables rapid detection of functional Vδ1+ and Vδ2+ γδ T cells
Eur. J. Immunol. 2022 May;52(5):730-736.
Butyrophilins: γδ T Cell Receptor Ligands, Immunomodulators and More
Front Immunol. 2022 Mar 17;13:876493
Stimulatory and inhibitory activity of STING ligands on tumor-reactive human gamma/delta T cells
Oncoimmunology. 2022 Feb 1;11(1):2030021.
2021
αβ T cells replacing dermal and epidermal γδ T cells in Tcrd-/- mice express an MHC-independent TCR repertoire
Eur J Immunol. 2021 Nov;51(11):2618-2632.
Immuno-antibiotics: targeting microbial metabolic pathways sensed by unconventional T cells
Immunother Adv. 2021 Apr 5;1(1):ltab005
A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Sci Immunol. 2021 Apr 23;6:eabf0125.
Genetic Influence on the Peripheral Differentiation Signature of Vδ2+ γδ and CD4+ αβ T Cells in Adults
Cells. 2021 Feb 11;10(2):373.
Reply to: Vitamin C as a promoter of γδ T cells
Cell Mol Immunol. 2021 Feb;18(2):495.
Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer
Cell Mol Immunol. 2021 Feb;18:427-439
Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance
Mucosal Immunol. 2021 Jan;14:242-252.
Direct Regulation of the T Cell Antigen Receptors’s Activity by Cholesterol
Front Cell Dev Biol. 2021 Jan 8;8:615996.
Direct Regulation of the T Cell Antigen Receptor's Activity by Cholesterol
Front Cell Dev Biol. 2021 Jan 8;8:615996.
2020
A glance over the fence: Using phylogeny and species comparison for a better understanding of antigen recognition by human γδ T-cells
Immunol Rev. 2020 Nov;298(1):218-236.
From basic research to clinical application of γδ T cells
Immunol Rev. 2020 Nov;298(1):5-9.
Tumor resistance mechanisms and their consequences on γδ T cell activation
Immunol Rev. 2020 Nov;298:84-98.
Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions
Cell Mol Immunol. 2020 Sep;17(9):914-924.
Cancer immunotherapy with γδ T cells: many paths ahead of us
Cell Mol Immunol. 2020 Sept;17:925-939.
Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth
Proc Natl Acad Sci U S A. 2020 Aug 4;117:18649-18660.
Galectin-3 Released by Pancreatic Ductal Adenocarcinoma Suppresses γδ T Cell Proliferation but Not Their Cytotoxicity
Front Immunol. 2020 Jun 30;11:1328.
An Update on the Molecular Basis of Phosphoantigen Recognition by Vγ9Vδ2 T Cells
Cells. 2020 Jun 9;9(6):1433.
Immune Signatures and Survival of Patients With Metastatic Melanoma, Renal Cancer, and Breast Cancer
Front Immunol. 2020 June 9;11:1152.
A comparative view on vitamin C effects on αβ- versus γδ T-cell activation and differentiation
J Leukoc Biol. 2020 Jun;107:1009-1022.
TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults
J Leukoc Biol. 2020 Jun;107(6):1023-1032
αβ and γδ T cell receptors: Similar but different.
J Leukoc Biol. 2020 Jun;107:1045-1055.
Pitfalls in the characterization of circulating and tissue-resident human γδ T cells
J Leukoc Biol. 2020 Jun;107:1097-1105.
Bispecific antibodies enhance tumor-infiltrating T cell cytotoxicity against autologous HER-2-expressing high-grade ovarian tumors
J Leukoc Biol. 2020 Jun;107:1081-1095.
Resolving the mystery-How TCR transgenic mouse models shed light on the elusive case of gamma delta T cells
J Leukoc Biol. 2020 Jun;107:993-1007.
Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells
Cells. 2020 May 6;9:1140.
Accurate determination of γδ T cells in multi-channel mass and flow cytometry
Cytometry B Clin Cytom. 2021 May;100(3):288-289.
Vitamin C promotes the proliferation and effector functions of human γδ T cells
Cell Mol Immunol. 2020 May;17:462-473.
Vitamin C supports conversion of human γδ T cells into FOXP3-expressing regulatory cells by epigenetic regulation
Sci Rep. 2020 Apr 16;10:6550.
Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
Immunity. 2020 Mar 17;52(3):487-498.e6
Human γδ TCR Repertoires in Health and Disease
Cells. 2020 Mar 26;9(4):800.
Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset
Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6697-6707.
Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
Nat Rev Drug Discov. 2020 Mar;19:169-184.
2019
The TCR is an allosterically regulated macromolecular machinery changing its conformation while working
Immunol Rev. 2019 Sep;291:8-25.
TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells
Front Immunol. 2019 Aug 28;10:2044.
Dangerous γδ T cells in aged mice
EMBO Rep. 2019 Aug;20:e48678
High-throughput analysis of the human thymic Vδ1+ T cell receptor repertoire
Sci Data. 2019 Jul 4;6:115.
Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells
Cell Rep. 2019 Jun 18;27:3657-3671.e4.
Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function
Eur J Immunol. 2019;49:686-693.