7th September 2022, Hannover - Germany

The Satellite Symposium on Innate and Adaptive Signals received via the γδ TCR and αβ TCR was  organized by the γδ T cell research group (FOR2799) on 7th September as part of the upcoming joined Symposium of the DGFI & ÖGAI in Hannover.   

During the Symposium, we discussed and compared αβ versus γδ TCR signaling and ligands, their innate versus adaptive functions, development, tissue-residency and therapeutic applications.   

With Yueh-hsiu Chien and Mark Davis (both from Stanford) who co-discovered the γδ and αβ TCR, respectively, Peter Steinberger (Med University Vienna) and Wolfgang Schamel (University of Freiburg) we were happy to have attracted four excellent key note speakers. 

09:30 - 09:35

Welcome

Immo Prinz (Hamburg, Germany)

Sarina Ravens (Hannover, Germany)

09:35 - 10:05

What makes gamma delta T cell innate-like reactivity possible?

Yueh-hsiu Chien (Stanford, United States)

10:05 - 10:35

Developmental dynamics of unconventional T cells

Andreas Krueger (Justus Liebig University Gießen) 

10:35 - 10:55

The TCR repertoire of the largest unconventional T-cell population in human cord blood is imprinted by agonist selection

Guillem Sánchez Sánchez (Université Libre de Bruxelles) 

10:55 - 12:00

Coffee Break/Poster Session/Networking

Poster 1: Division of labor and cooperation between protein regions localized on different butyrophilin proteins controls phosphoantigen-mediated activation of human γδ T cells

Thomas Herrmann (University of Würzburg)

Poster 2: Kidney‐resident innate‐like memory γδ T cells control chronic Staphylococcus aureus infection

Hans-Willi Mittrücker (University Medical Center Hamburg-Eppendorf)

Poster 3: The role of CXCR6+ γδ T cells in chronic hepatitis B virus (HBV) infection

Katja Steppich (Hannover Medical School)

Poster 4: Deciphering the epigenetic regulation and age-dependent heterogeneity of Vγ4+ T cells

Tao Yang (Hannover Medical School)

Poster 5: Investigating the potential of CAR – γδ T cells as an alternative to treat γδ T-cell lymphomas

Kristian Leonard Jack Thomson (University of Göttingen)

Poster 6: Difference between peripheral blood and tumor-infiltrating γδ T cells of ovarian cancer patients

Hans-Heinrich Oberg (University of Kiel)

12:00 - 12:30

Regulatory CD8 T cells in autoimmunity and infection

Mark M. Davis (Stanford Medicine)

12:30 - 13:00

TCR recognition, CAR signaling and co-stimulation – new insights obtained with a Jurkat reporter platform

Peter Steinberger (Vienna, Austria)

13:00 - 13:30

Optogenetics: activation of the gamma delta TCR is controlled by kinetic proofreading

Wolfgang Schamel (Albert Ludwigs University Freiburg) 

Hannover Medical School

Carl-Neuberg-Straße 1

30625 Hannover

Lecture Hall F (Plenary Hall)