FOR2799 Receiving&Translating Signals via the γδ T Cell Receptor
FOR2799 Receiving&Translating Signals via the γδ T Cell Receptor
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7th September 2022, Hannover - Germany

Satellite Symposium on "Innate and Adaptive Signals received via the γδ TCR and αβ TCR"

The Satellite Symposium on Innate and Adaptive Signals received via the γδ TCR and αβ TCR was  organized by the γδ T cell research group (FOR2799) on 7th September as part of the upcoming joined Symposium of the DGFI & ÖGAI in Hannover.   


During the Symposium, we discussed and compared αβ versus γδ TCR signaling and ligands, their innate versus adaptive functions, development, tissue-residency and therapeutic applications.   


With Yueh-hsiu Chien and Mark Davis (both from Stanford) who co-discovered the γδ and αβ TCR, respectively, Peter Steinberger (Med University Vienna) and Wolfgang Schamel (University of Freiburg) we were happy to have attracted four excellent key note speakers. 

Program

09:30 - 09:35

Welcome

Immo Prinz (Hamburg, Germany)

Sarina Ravens (Hannover, Germany)


09:35 - 10:05

What makes gamma delta T cell innate-like reactivity possible?

Yueh-hsiu Chien (Stanford, United States)


10:05 - 10:35

Developmental dynamics of unconventional T cells

Andreas Krueger (Justus Liebig University Gießen) 


10:35 - 10:55

The TCR repertoire of the largest unconventional T-cell population in human cord blood is imprinted by agonist selection

Guillem Sánchez Sánchez (Université Libre de Bruxelles) 


10:55 - 12:00

Coffee Break/Poster Session/Networking


Poster 1: Division of labor and cooperation between protein regions localized on different butyrophilin proteins controls phosphoantigen-mediated activation of human γδ T cells

Thomas Herrmann (University of Würzburg)


Poster 2: Kidney‐resident innate‐like memory γδ T cells control chronic Staphylococcus aureus infection

Hans-Willi Mittrücker (University Medical Center Hamburg-Eppendorf)


Poster 3: The role of CXCR6+ γδ T cells in chronic hepatitis B virus (HBV) infection

Katja Steppich (Hannover Medical School)


Poster 4: Deciphering the epigenetic regulation and age-dependent heterogeneity of Vγ4+ T cells

Tao Yang (Hannover Medical School)


Poster 5: Investigating the potential of CAR – γδ T cells as an alternative to treat γδ T-cell lymphomas

Kristian Leonard Jack Thomson (University of Göttingen)


Poster 6: Difference between peripheral blood and tumor-infiltrating γδ T cells of ovarian cancer patients

Hans-Heinrich Oberg (University of Kiel)


12:00 - 12:30

Regulatory CD8 T cells in autoimmunity and infection

Mark M. Davis (Stanford Medicine)


12:30 - 13:00

TCR recognition, CAR signaling and co-stimulation – new insights obtained with a Jurkat reporter platform

Peter Steinberger (Vienna, Austria)


13:00 - 13:30

Optogenetics: activation of the gamma delta TCR is controlled by kinetic proofreading

Wolfgang Schamel (Albert Ludwigs University Freiburg) 


Location

Hannover Medical School

Carl-Neuberg-Straße 1

30625 Hannover


Lecture Hall F (Plenary Hall)

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