The Satellite Symposium on Innate and Adaptive Signals received via the γδ TCR and αβ TCR was organized by the γδ T cell research group (FOR2799) on 7th September as part of the upcoming joined Symposium of the DGFI & ÖGAI in Hannover.
During the Symposium, we discussed and compared αβ versus γδ TCR signaling and ligands, their innate versus adaptive functions, development, tissue-residency and therapeutic applications.
With Yueh-hsiu Chien and Mark Davis (both from Stanford) who co-discovered the γδ and αβ TCR, respectively, Peter Steinberger (Med University Vienna) and Wolfgang Schamel (University of Freiburg) we were happy to have attracted four excellent key note speakers.
09:30 - 09:35
Welcome
Immo Prinz (Hamburg, Germany)
Sarina Ravens (Hannover, Germany)
09:35 - 10:05
What makes gamma delta T cell innate-like reactivity possible?
Yueh-hsiu Chien (Stanford, United States)
10:05 - 10:35
Developmental dynamics of unconventional T cells
Andreas Krueger (Justus Liebig University Gießen)
10:35 - 10:55
The TCR repertoire of the largest unconventional T-cell population in human cord blood is imprinted by agonist selection
Guillem Sánchez Sánchez (Université Libre de Bruxelles)
10:55 - 12:00
Coffee Break/Poster Session/Networking
Poster 1: Division of labor and cooperation between protein regions localized on different butyrophilin proteins controls phosphoantigen-mediated activation of human γδ T cells
Thomas Herrmann (University of Würzburg)
Poster 2: Kidney‐resident innate‐like memory γδ T cells control chronic Staphylococcus aureus infection
Hans-Willi Mittrücker (University Medical Center Hamburg-Eppendorf)
Poster 3: The role of CXCR6+ γδ T cells in chronic hepatitis B virus (HBV) infection
Katja Steppich (Hannover Medical School)
Poster 4: Deciphering the epigenetic regulation and age-dependent heterogeneity of Vγ4+ T cells
Tao Yang (Hannover Medical School)
Poster 5: Investigating the potential of CAR – γδ T cells as an alternative to treat γδ T-cell lymphomas
Kristian Leonard Jack Thomson (University of Göttingen)
Poster 6: Difference between peripheral blood and tumor-infiltrating γδ T cells of ovarian cancer patients
Hans-Heinrich Oberg (University of Kiel)
12:00 - 12:30
Regulatory CD8 T cells in autoimmunity and infection
Mark M. Davis (Stanford Medicine)
12:30 - 13:00
TCR recognition, CAR signaling and co-stimulation – new insights obtained with a Jurkat reporter platform
Peter Steinberger (Vienna, Austria)
13:00 - 13:30
Optogenetics: activation of the gamma delta TCR is controlled by kinetic proofreading
Wolfgang Schamel (Albert Ludwigs University Freiburg)
Hannover Medical School
Carl-Neuberg-Straße 1
30625 Hannover
Lecture Hall F (Plenary Hall)
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